The Cannabis Terpene that Can Kill Cancer Cells – Terpineol
Researchers at the University of British Columbia have identified the genetic components of marijuana that give the herb its aromas and flavors: source
29-MAR-2017…[Jörg] Bohlmann, graduate student Judith Booth, and Jonathan Page, an adjunct professor in the botany department who founded the cannabis testing and biotechnology company Anandia Labs…found about 30 terpene synthase genes that contribute to diverse flavors in cannabis. This number is comparable to similar genes that play a role in grapevine flavor for the wine industry. The genes the researchers discovered play a role in producing natural products like limonene, myrcene, and pinene in the cannabis plants. These fragrant molecules are generally known in the industry as terpenes.
“The limonene compound produces a lemon-like flavor and myrcene produces the dank, earthy flavor characteristic of purple kush,” said Booth….They also found a gene that produces the signature terpene of cannabis, beta-caryophyllene, which interacts with cannabinoid receptors in human cells along with other active ingredients in cannabis.
Bohlmann says the economic potential of a regulated cannabis industry is huge, but a current challenge is that growers are working with a crop that is not well standardized and highly variable for its key natural product profiles…”There is a need for high-quality and consistent products made from well-defined varieties.” he said.
The researchers say it will also be important to examine to what extent terpene compounds might interact with the cannabinoid compounds such as tetrahydrocannabinol (THC) that confer the medicinal properties of cannabis.
☛ AAAS Public Release: Researchers identify genes that give cannabis its flavor
☛ Original Publication: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173911
Is this a case of Science following Stoners?
1.Limonen…………..7. Alpha-Pinene / Beta-Pinene
3. Linalool…………..9. Terpineol
4. Alpha Bisabolol....10. Caryophyllene
5. Delta 3 Carene…..11. Camphene
- ☛ Introduction to Terpenes
- learn how terpenes work synergistically with cannabinoids It is well established that cannabis is capable of affecting the mind, emotions and behavior. The main psychotropic cannabinoid, delta-9-tetrahydrocannabinol (THC) has been intensely studied. However, many of the other cannabinoids, terpenoids and flavonoids found in medical marijuana that play a big role in boosting the therapeutic effect of cannabis remain understudied.
The Carlini et al study demonstrated that there may be potentiation (a form of synaptic plasticity that is known to be important for learning and memory) of the effects of THC by other substances present in cannabis. The double-blind study found that cannabis with equal or higher levels of CBD and CBN to THC induced effects two to four times greater than expected from THC content alone. The effects of smoking twice as much of a THC-only strain were no different than that of the placebo.