Notice they can rebirth Thalidomide in month's. Now it is found that second generation babies born with flippers from Granma's given thalidomide...Cancer treatment? Anorexia in teenage girls? AIDs wasting anything but cannabis taking away their profits...Thats D.E.A.th, thats WoD!
Peace, Love and Liberty
DdC
Cannabis Less Risky Than Alcohol/Tobacco, Says Report
pub3.ezboard.com/fendingc...=340.topic
Feds Clash with San Francisco Over Marijuana
pub3.ezboard.com/fendingc...=339.topic
Coalition for Compassionate Access
www.compassionateaccess.o...mesad.html
No Attrition in Research on Wasting Therapies
gmhc.org/living/treatment...1045h.html
Thalidomide: New Results
In January, a thalidomide developer, Celgene, of Warren, New Jersey, announced that the data from its trial in 99 people with AIDS wasting showed a statistically significant weight gain. The company seems to have "jumped the gun," as one person close to the trial put it. No data were yet available from the trial to justify Celgene's press release.
Drug company rebuked for marketing thalidomide as cancer fighter
www.wcanews.com/archives/...l1700c.htm
In 1957, the drug thalidomide was approved for use in Europe as a treatment for morning sickness caused by pregnancy. Thousands of women took the pills, assured by the drug maker that they were safe.
Unfortunately, the drugs had primarily been tested as a sleep aid for elderly patients -- not on pregnant women. By the time its tragic side effects were known, it was too late to help the than 12,000 babies born with severe birth defects.
Today, it is known that even one capsule of thalidomide can cause devastating defects, including the development of flipper-like limbs.
Yet, the Celgene Corporation has promoted the pill as a cancer treatment, despite warnings from the FDA.
On July 16, 1998, the FDA gave Celgene approval to market its brand of thalidomide -- Thalomid -- for the treatment of leprosy. It specifically told the company that "statements or implications by you that this product may indeed be safe and efficacious in the treatment of diseases or patient populations beyond that approved in your application may be considered a violation of the promotional provisions of the Act."
Just two weeks later, the FDA had to contact Celgene to discuss concerns that the company's promotional materials contained references to unapproved uses of thalidomide.
On Nov. 9, 1998, the FDA issued a letter to Celgene about several press releases it was distributing. "Those press releases were misleading (lacked fair balance) in that they presented little or no risk information," the FDA warned.
Despite repeated warnings, the FDA says Celgene has continued to promote the dangerous drug to the medical community for unapproved uses.
According to an FDA letter to Celgene dated April 21, 2000, "Celgene has also represented to physicians that Thalomid can be used to treat various cancers, for cancer patient 'weight loss,' and to promote a feeling of'general well-being' in these same patients."
At a luncheon held by Celgene for an oncology practice group, a sales representative reportedly told doctors that thalidomide is "good for weight loss," that it could be used "as an appetite stimulant," and that it is a "great drug for feelings of general well-being." When asked if thalidomide had FDA approval for these uses, the sales representative stated "no, but do you want some material anyway?"
SOURCE: Warning Letter to Celgene Corporation, Food and Drug Administration, April 21, 2000.
Nutrition and Wasting by Brenda Lein
www.projinf.org/pub/15/fu...#nutrition
Appetite Stimulants
In addition to adjusting eating habits and diet, some people find they need appetite stimulants in order to maintain weight and good nutrition. Many people believe that marijuana may be useful to stimulate appetite and calm the stomach. Smoking marijuana can be hard on the lungs so some people prefer baking it into brownies or truffles. The chemical agent in marijuana, THC, has been synthesized and is the active agent in Marinol, which is FDA approved as an appetite stimulant for people with HIV. Absorption of Marinol is problematic. Sometimes it works perfectly, sometimes not at all and still other times it works a little too well, leaving folks too euphoric or "stoned" to carry on with planned activities.
An older drug, thalidomide, inhibits TNF and reduces viral replication in test tubes. Several studies of thalidomide are ongoing in HIV, one to examine its benefits in treating HIV-related aphthous ulcers, one in HIV-related wasting syndrome and another to examine its antiviral effects. Other approaches to lowering TNF levels, including synthetic antibodies against TNF and soluble TNF receptors, are being tested at the National Cancer Institute and in Canada.
Company Warned NOT to Promote Thalidomide for Treatment of Multiple Myeloma
www.cancerpage.com/cancer...ews835.htm
Moreover, during a December 22, 1998 meeting with the company, the agency expressed "strong concern" about Celgene's practice of distributing materials regarding unapproved Thalomid uses and about company press releases, which omitted the drug's risk information.
Department of Health and Human Services
Research Plan Portion of Public Health Service Grant Application
submitted April 1996
Protocol: Smoked Marijuana for HIV-Associated Anorexia and Wasting
www.maps.org/mmj/abrams2.shtml
Institute of Medicine
The Medical Value of Marijuana and Related Substances
books.nap.edu/html/marimed/ch4.html
During the course of drug development, a typical compound is found to have some medical benefit and then extensive tests are undertaken to determine its safety and proper dosage for medical use. In contrast, marijuana has been widely used in the United States for decades. In 1996, 68.6 million people--32% of the U.S. population over 12 years old--had tried marijuana or hashish at least once; 5% were current users.
The data on the adverse effects of marijuana are more extensive than the data on its effectiveness. Clinical studies of marijuana are difficult to conduct: researchers interested in clinical studies of marijuana face a series of barriers, research funds are limited, and there is a daunting thicket of regulations to be negotiated at the federal level (those of the Food and Drug Administration, FDA, and the Drug Enforcement Agency, DEA) and state levels (see chapter 5). Consequently, the rapid growth in basic research on cannabinoids contrasts with the paucity of substantial clinical studies on medical uses.
This chapter is devoted to an analysis of the therapeutic value of marijuana and cannabinoids for specific symptoms associated with various conditions. The risks associated with the medical use of marijuana are discussed in chapter 3. It should be noted that THC, the primary active ingredient in marijuana, is an FDA-approved drug referred to as dronabinol and marketed as Marinol. Marijuana is advocated primarily for relief from the symptoms of disease rather than as a cure.
JAMA HIV/AIDs Research Center
Improving the Management of HIV Disease
www.ama-assn.org/special/...abrams.htm
Marijuana, either inhaled or ingested in the form of dronabinol capsules, has also been widely used as an appetite stimulant by persons with HIV disease. As of July, the Cannabis Buyers' Club in San Francisco (shut down in August) made this drug available to approximately 8000 people with HIV disease and other life-threatening medical conditions. Based on reports of patients' preferences for inhaled marijuana because of the ability to titrate onset of appetite and duration effect, researchers at the University of California San Francisco designed a clinical trial to compare three strains of inhaled marijuana with dronabinol. Although the study protocol was approved by the FDA and the institutional review board, questions regarding the source of the marijuana to be used have caused significant delays.
Is the government's war against marijuana justified as public
policy?
Lynn Zimmer vs Mark Souder
www.findarticles.com/cf_0...rint.jhtml
Shalalagans
www.cannabinoid.com/wwwbo.../28670.gif
Moldy Propagandist
www.cannabinoid.com/board.../35025.gif
Microbio-illogical contaminants on cannabis
www.cannabinoid.com/board.../35023.gif
THALIDOMIDE: POTENTIAL BENEFITS AND RISKS
www.fda.gov/oashi/patrep/nih910.html
IEN-Indigenous Environmental Network Links
pub3.ezboard.com/fendingc...D=16.topic
Corporate Predators...
pub3.ezboard.com/fendingc...D=17.topic
JC/DC
pub3.ezboard.com/fendingc...D=76.topic
boards.marihemp.com/board.../40295.gif
The Tuskegee Syphilis Experiment & Linx
pub3.ezboard.com/fendingc...=341.topic
boards.marihemp.com/board.../40342.jpg
Bushit Cheneynagans D.E.A.th & Oil!
pub3.ezboard.com/fendingc...D=53.topic
Farben's Bushit Circus
boards.marihemp.com/board.../39401.gif
Farben's Bushit Circus Still In Town
boards.marihemp.com/board...ml?1x39400
D.E.A.th Deceptions
www.angelfire.com/ca7/ddc/DEAth.html
www.cannabinoid.com/board.../39670.gif
Anslinger-Bush-Hearst-Nixon-Hitler-Dj v!!!
pub3.ezboard.com/fendingc...D=55.topic
National Missile Defense: Blowing The Whistle On Bad Science
pub3.ezboard.com/fendingc...=338.topic
Amerika, Amerika by Claire Wolfe
pub3.ezboard.com/fendingc...D=40.topic
Peace, Love and Liberty
DdC
Cannabis Less Risky Than Alcohol/Tobacco, Says Report
pub3.ezboard.com/fendingc...=340.topic
Feds Clash with San Francisco Over Marijuana
pub3.ezboard.com/fendingc...=339.topic
Coalition for Compassionate Access
www.compassionateaccess.o...mesad.html
No Attrition in Research on Wasting Therapies
gmhc.org/living/treatment...1045h.html
Thalidomide: New Results
In January, a thalidomide developer, Celgene, of Warren, New Jersey, announced that the data from its trial in 99 people with AIDS wasting showed a statistically significant weight gain. The company seems to have "jumped the gun," as one person close to the trial put it. No data were yet available from the trial to justify Celgene's press release.
Drug company rebuked for marketing thalidomide as cancer fighter
www.wcanews.com/archives/...l1700c.htm
In 1957, the drug thalidomide was approved for use in Europe as a treatment for morning sickness caused by pregnancy. Thousands of women took the pills, assured by the drug maker that they were safe.
Unfortunately, the drugs had primarily been tested as a sleep aid for elderly patients -- not on pregnant women. By the time its tragic side effects were known, it was too late to help the than 12,000 babies born with severe birth defects.
Today, it is known that even one capsule of thalidomide can cause devastating defects, including the development of flipper-like limbs.
Yet, the Celgene Corporation has promoted the pill as a cancer treatment, despite warnings from the FDA.
On July 16, 1998, the FDA gave Celgene approval to market its brand of thalidomide -- Thalomid -- for the treatment of leprosy. It specifically told the company that "statements or implications by you that this product may indeed be safe and efficacious in the treatment of diseases or patient populations beyond that approved in your application may be considered a violation of the promotional provisions of the Act."
Just two weeks later, the FDA had to contact Celgene to discuss concerns that the company's promotional materials contained references to unapproved uses of thalidomide.
On Nov. 9, 1998, the FDA issued a letter to Celgene about several press releases it was distributing. "Those press releases were misleading (lacked fair balance) in that they presented little or no risk information," the FDA warned.
Despite repeated warnings, the FDA says Celgene has continued to promote the dangerous drug to the medical community for unapproved uses.
According to an FDA letter to Celgene dated April 21, 2000, "Celgene has also represented to physicians that Thalomid can be used to treat various cancers, for cancer patient 'weight loss,' and to promote a feeling of'general well-being' in these same patients."
At a luncheon held by Celgene for an oncology practice group, a sales representative reportedly told doctors that thalidomide is "good for weight loss," that it could be used "as an appetite stimulant," and that it is a "great drug for feelings of general well-being." When asked if thalidomide had FDA approval for these uses, the sales representative stated "no, but do you want some material anyway?"
SOURCE: Warning Letter to Celgene Corporation, Food and Drug Administration, April 21, 2000.
Nutrition and Wasting by Brenda Lein
www.projinf.org/pub/15/fu...#nutrition
Appetite Stimulants
In addition to adjusting eating habits and diet, some people find they need appetite stimulants in order to maintain weight and good nutrition. Many people believe that marijuana may be useful to stimulate appetite and calm the stomach. Smoking marijuana can be hard on the lungs so some people prefer baking it into brownies or truffles. The chemical agent in marijuana, THC, has been synthesized and is the active agent in Marinol, which is FDA approved as an appetite stimulant for people with HIV. Absorption of Marinol is problematic. Sometimes it works perfectly, sometimes not at all and still other times it works a little too well, leaving folks too euphoric or "stoned" to carry on with planned activities.
An older drug, thalidomide, inhibits TNF and reduces viral replication in test tubes. Several studies of thalidomide are ongoing in HIV, one to examine its benefits in treating HIV-related aphthous ulcers, one in HIV-related wasting syndrome and another to examine its antiviral effects. Other approaches to lowering TNF levels, including synthetic antibodies against TNF and soluble TNF receptors, are being tested at the National Cancer Institute and in Canada.
Company Warned NOT to Promote Thalidomide for Treatment of Multiple Myeloma
www.cancerpage.com/cancer...ews835.htm
Moreover, during a December 22, 1998 meeting with the company, the agency expressed "strong concern" about Celgene's practice of distributing materials regarding unapproved Thalomid uses and about company press releases, which omitted the drug's risk information.
Department of Health and Human Services
Research Plan Portion of Public Health Service Grant Application
submitted April 1996
Protocol: Smoked Marijuana for HIV-Associated Anorexia and Wasting
www.maps.org/mmj/abrams2.shtml
Institute of Medicine
The Medical Value of Marijuana and Related Substances
books.nap.edu/html/marimed/ch4.html
During the course of drug development, a typical compound is found to have some medical benefit and then extensive tests are undertaken to determine its safety and proper dosage for medical use. In contrast, marijuana has been widely used in the United States for decades. In 1996, 68.6 million people--32% of the U.S. population over 12 years old--had tried marijuana or hashish at least once; 5% were current users.
The data on the adverse effects of marijuana are more extensive than the data on its effectiveness. Clinical studies of marijuana are difficult to conduct: researchers interested in clinical studies of marijuana face a series of barriers, research funds are limited, and there is a daunting thicket of regulations to be negotiated at the federal level (those of the Food and Drug Administration, FDA, and the Drug Enforcement Agency, DEA) and state levels (see chapter 5). Consequently, the rapid growth in basic research on cannabinoids contrasts with the paucity of substantial clinical studies on medical uses.
This chapter is devoted to an analysis of the therapeutic value of marijuana and cannabinoids for specific symptoms associated with various conditions. The risks associated with the medical use of marijuana are discussed in chapter 3. It should be noted that THC, the primary active ingredient in marijuana, is an FDA-approved drug referred to as dronabinol and marketed as Marinol. Marijuana is advocated primarily for relief from the symptoms of disease rather than as a cure.
JAMA HIV/AIDs Research Center
Improving the Management of HIV Disease
www.ama-assn.org/special/...abrams.htm
Marijuana, either inhaled or ingested in the form of dronabinol capsules, has also been widely used as an appetite stimulant by persons with HIV disease. As of July, the Cannabis Buyers' Club in San Francisco (shut down in August) made this drug available to approximately 8000 people with HIV disease and other life-threatening medical conditions. Based on reports of patients' preferences for inhaled marijuana because of the ability to titrate onset of appetite and duration effect, researchers at the University of California San Francisco designed a clinical trial to compare three strains of inhaled marijuana with dronabinol. Although the study protocol was approved by the FDA and the institutional review board, questions regarding the source of the marijuana to be used have caused significant delays.
Is the government's war against marijuana justified as public
policy?
Lynn Zimmer vs Mark Souder
www.findarticles.com/cf_0...rint.jhtml
Shalalagans
www.cannabinoid.com/wwwbo.../28670.gif
Moldy Propagandist
www.cannabinoid.com/board.../35025.gif
Microbio-illogical contaminants on cannabis
www.cannabinoid.com/board.../35023.gif
THALIDOMIDE: POTENTIAL BENEFITS AND RISKS
www.fda.gov/oashi/patrep/nih910.html
IEN-Indigenous Environmental Network Links
pub3.ezboard.com/fendingc...D=16.topic
Corporate Predators...
pub3.ezboard.com/fendingc...D=17.topic
JC/DC
pub3.ezboard.com/fendingc...D=76.topic
boards.marihemp.com/board.../40295.gif
The Tuskegee Syphilis Experiment & Linx
pub3.ezboard.com/fendingc...=341.topic
boards.marihemp.com/board.../40342.jpg
Bushit Cheneynagans D.E.A.th & Oil!
pub3.ezboard.com/fendingc...D=53.topic
Farben's Bushit Circus
boards.marihemp.com/board.../39401.gif
Farben's Bushit Circus Still In Town
boards.marihemp.com/board...ml?1x39400
D.E.A.th Deceptions
www.angelfire.com/ca7/ddc/DEAth.html
www.cannabinoid.com/board.../39670.gif
Anslinger-Bush-Hearst-Nixon-Hitler-Dj v!!!
pub3.ezboard.com/fendingc...D=55.topic
National Missile Defense: Blowing The Whistle On Bad Science
pub3.ezboard.com/fendingc...=338.topic
Amerika, Amerika by Claire Wolfe
pub3.ezboard.com/fendingc...D=40.topic
